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Home » GATE Study Material » Pharmaceutical Science » Medicinal Chemistry » Radiopharmacology


Radiopharmacology


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Radiopharmacology

Technetium-99m

99mTc is a gamma emitter.

Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging
Tc99m-pertechnetate Thyroid uptake and thyroid imaging

Stomach and salivary gland imaging
Meckel's diverticulum imaging
Brain imaging
Micturating cystogram
First pass blood flow imaging
First pass peripheral vascular imaging

IV In-vivo Imaging
Tc99m-pertechnetate Lacrimal imaging Eye drops In-vivo Imaging
Tc99m-Human albumin Cardiac blood pool imaging IV In-vivo Imaging
Tc99m-Human albumin Peripheral vascular imaging IV In-vivo Imaging
Tc99m-Human albumin macroaggregates or microspheres Lung perfusion imaging IV In-vivo Imaging
Tc99m-Human albumin macroaggregates or microspheres Lung perfusion imaging with venography IV In-vivo Imaging
Tc99m-Phosphonates and phosphates Bone imaging IV In-vivo Imaging
Tc99m-Phosphonates and phosphates Myocardial imaging IV In-vivo Imaging
Tc99m-TPA (diethylenetriaminepenta-acetic acid) Renal imaging
First pass blood flow studies
Brain imaging
IV In-vivo Imaging
Tc99m-TPA (diethylenetriaminepenta-acetic acid) Lung ventilation imaging Aerosol inhalation In-vivo Imaging
Tc99m-DMSA(V) (dimercaptosuccinic acid) Tumour imaging IV In-vivo Imaging
Tc99m-DMSA(III) (dimercaptosuccinic acid) Renal imaging IV In-vivo Imaging
Tc99m-Colloid Bone marrow imaging

GI Bleeding

IV In-vivo Imaging
Tc99m-Colloid Lymph node imaging Interstitial In-vivo Imaging
Tc99m-Colloid Oesophageal transit and reflux imaging Oral In-vivo Imaging
Tc99m-Colloid Lacrimal imaging Eye drops In-vivo Imaging
Tc99m-HIDA (Hepatic iminodiacetic acid) Functional biliary system imaging IV In-vivo Imaging
Tc99m-Denatured red bood cells Red cell volume IV In-vitro Non-imaging
Tc99m-Red blood cells GI bleeding

Cardiac blood pool imaging
Peripheral vascular imaging

IV In-vivo Imaging
Tc99m-MAG3 (mercaptoacetyltriglycine) Renal imaging

First pass blood flow imaging

IV In-vivo Imaging
Tc99m-HMPAO (Hexamethyl-propylene amine oxime) Cerebral blood flow imaging IV In-vivo Imaging
Tc99m-HMPAO (Hexamethyl-propylene amine oxime) labelled leucocytes Infection/inflammation imaging IV In-vivo Imaging
Tc99m-estamibi Parathyroid imaging

Non-specific tumour imaging
Thyroid tumour imaging
Breast imaging
Myocardial imaging

IV In-vivo Imaging
Tc99m-Sulesomab (IMMU-MN3 murine Fab'-SH antigranulocyte monoclonal antibody fragments) Infection/inflammation imaging IV In-vivo Imaging
Tc99m-Technegas Lung ventilation imaging Inhalation In-vivo Imaging
Tc99m-Human immunoglobulin Infection/inflammation imaging IV In-vivo Imaging
Tc99m-Tetrofosmin Parathyroid imaging

Myocardial imaging

IV In-vivo Imaging
Tc99m-ECD (ethyl cysteinate dimer) Brain imaging IV In-vivo Imaging

Thallium-201

201Tl is a gamma emitter.

Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging
Tl201-Tl+ Non-specific tumour imaging

Thyroid tumour imaging
Myocardial imaging
Parathyroid imaging

IV In-vivo Imaging

Xenon-133

133Xe is a gamma emitter.

Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging
Xe133-gas Lung ventilation studies Inhalation In-vivo Imaging
Xe133 in isotonic sodium chloride solution Cerebral blood flow IV In-vivo Imaging

Yttrium-90

90Y is a beta emitter.

Name Treatment of Route of administration
Y90-Silicate Arthritic conditions Intra-articular
Y90-Silicate Malignant disease Intracavitary
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