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Home » GATE Study Material » Pharmaceutical Science » Medicinal Chemistry » Radiopharmacology


Radiopharmacology


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Radiopharmacology

Radiopharmacology

is the study and preparation of radiopharmaceuticals, which are radioactive pharmaceuticals. Radiopharmaceuticals are used in the field of nuclear medicine as tracers in the diagnosis and treatment of many diseases. Many radiopharmaceuticals use technetium (Tc-99m). In the book Technetium by Klaus Schwochau, 31 different radiopharmaceuticals based on Tc-99m are listed for imaging and functional studies of the brain, myocardium, thyroid, lungs, liver, gallbladder, kidneys, skeleton, blood and tumors.



A list of nuclear medicine radiopharmaceuticals follows. Some radioisotopes are used in ionic or inert form without attachment to a pharmaceutical, these are also included. There is a section for each radioisotope with a table of radiopharmaceuticals using that radioisotope. The sections are ordered alphabetically by the English name of the radioisotope. Sections for the same element are then ordered by atomic mass number.

Calcium-47

47Ca is a beta and gamma emitter.

Name Invest igation Route of admini stration In-vitro / in-vivo Imaging / non- imaging
Ca-47 -Ca2+ Bone meta bolism IV In- vitro Non- imaging

Carbon -11

11C is a positron emitter.

Name Investi gation Route of admini stration In-vitro / in-vivo Imaging / non- imaging
C11-L -methyl- methi onine Brain tumour imaging

Para thyroid imag ing

IV In- vivo Imag ing

Carbon -14

14C is a beta emitter.

Name Investi gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
C14- Glyco cholic acid Breath test for small inte stine bacte rial over growth Oral In- vitro Non- imaging
C14- PABA (para- amino benzoic acid) Pan creatic studies Oral In- vitro Non- imaging
C14-Urea Breath test to detect Helico bacter pylori Oral In- vitro Non- imaging
C14 -d- xylose Breath test for small inte stine bact erial over growth Oral In- vitro Non- imaging

Chro mium -51

51Cr is a gamma emitter.

Name Inve sti gation Route of admini stration In-vitro / in- vivo Imaging / non- imaging
Cr51 -Red blood cells Red cell volume; sites of seque stra tion; gastro inte stinal blood loss IV In- vitro Non- imaging
Cr51-Cr3+ Gastro inte stinal protein loss IV In- vitro Non- imaging
Cr51 -EDTA (ethylene diaminete traacetic acid) Glome rular fil tration rate measur ement IV In- vitro Non- imaging

Cobalt -57

57Co is a gamma emitter.

Name Inve sti gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
Co57-Cyan ocoba lamin (vitamin B12) Ga stroin testinal absor ption Oral In- vitro Non- imaging

Cobalt -58

58Co is a gamma emitter.

Name Investi gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
Co58 -Cyano coba lamin (vitamin B12) Gastro inte stinal absor ption Oral In- vitro Non- imaging

Erbium -169

169Er is a beta emitter.

Name Trea tment of Route of admini stration
Er169- Colloid Arthritic conditions Intra- articular
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