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Home » GATE Study Material » Pharmaceutical Science » Medicinal Chemistry » Radiopharmacology


Radiopharmacology


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Radiopharmacology

Fluorine -18

18F is a positron emitter.

Name Investi gation Route of admini stra tion In- vitro / in- vivo Imaging / non- imaging
F18- FDG (Fluoro deoxy glucose) Tumour imaging

Myo cardial imaging

IV In- vivo Imaging
F18- Fluoride Bone imaging IV In- vivo Imaging


Gallium -67

67Ga is a gamma emitter. See Gallium scan.

Name Inve sti gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
Ga67- Ga3+ Tumour imaging IV In- vivo Imaging
Ga67 -Ga3+ Infec tion/ inflam mation imaging IV In- vivo Imaging

Hydrogen -3

3H or tritium is a beta emitter.

Name Inve sti gation Route of admini stration In- vitro / in- vivo Imaging / non-imaging
H3- water Total body water Oral or IV In- vitro Non- imaging

Indium -111

111In is a gamma emitter.

Name Inve sti gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
In111 -DTPA (iethyle netria mine penta- acetic acid) GI transit Oral In- vivo Imaging
In111 -DTPA (iethyle netria mine penta- acetic acid) Cister nogra phy Intra -ciste rnal In- vivo Imaging
In111- euco cytes Infec tion/ inflam mation imaging IV In- vivo Imaging
In111 -Pla telets Thrombus imaging IV In- vivo Imaging
In111-Pente treo tide Somato statin receptor imaging IV In- vivo Imaging

Iodine -123

123I is a gamma emitter.

Name Investi gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
I123- Iodide Thyroid uptake Oral or IV In- vivo Non- imaging
I123- Iodide Thyroid imaging

Thyroid metas tases imaging

Oral or IV In- vivo Imaging
I123 -o- Iodohip purate Renal imaging IV In- vivo Imaging
I123 -MIBG (m- iodo benzyl guani dine) Neuro ecto dermal tumour imaging IV In- vivo Imaging
I123 -FP- CIT SPECT imaging of Park inson's Disease IV In- vivo Imaging

Iodine -131

131I is a beta and gamma emitter.

Diagno stic

Name Investi gation Route of admini stration In- vitro / in- vivo Imaging / non- imaging
I131- Iodide Thyroid uptake Oral In- vivo Non- imaging
I131- Iodide Thyroid metas tases imaging Oral or IV In- vivo Imaging
I131- MIBG (m- iodob enzyl guani dine) Neuro ectod ermal tumour imaging IV In- vivo Imaging

Thera peutic

Name Trea tment of Route of admini stration
I131- Iodide Thyro toxi cosis IV or Oral
I131- Iodide Non- toxic goitre IV or Oral
I131- Iodide Thy roid carci noma IV or Oral
I131- MIBG (m- iodo benzyl guani dine) Mali gnant disease IV
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